Mutagenicity not determined target organ effects in clinical use target organ effects include the kidneys. Proprietary ingredients indicated as hazardous have been assessed under standards for workplace safety. Mannitol, usp grade exmn 50001 ops diagnostics llc. Cm0085 risk phrases safety phrases ec classification this product is not classified according to the eu regulations. Therefore, the test for bronchial hyperresponsiveness with mannitol should not be performed in any patient with clinically apparent asthma or very low baseline pulmonary function tests e. Pharmaceutical products safety data sheets fresenius kabi. Pharmaceutical products safety data sheets fresenius. The information provided on this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. Exposure controlspersonal protection exposure guidelines. Material safety data sheet dmannitol section 1 chemical product and company identification msds name.
Feb 24, 2020 pain and irritation where mannitol systemic goes into the body. The additional property of lipase activity of staphylococcus aureus can be detected by the addition of the. Laxative effects may occur if mannitol is consumed orally in large quantities. We continually provide comprehensive safety and regulatory data on our safety data sheets promoting safe usage and handling of our products. The information in mannitol e421 msds was obtained from current and reliable sources. Safety data sheet mannitol msds catalog service llc. Cm0399 risk phrases safety phrases ec classification this product is not classified according to the eu regulations. In case of skin contact wash off with soap and plenty of water. Inhaled mannitol acts as a bronchoconstrictor and may cause severe bronchospasm in susceptible patients. Methods and material for containment and cleaning up methods for cleaning up wear protective clothing as described in section 8 of this safety data sheet. Material safety data sheet canadian whmis classifications no information found this product has been classified in accordance with the hazard criteria of the controlled products. Jan 01, 2020 mannitol injection, usp is a parenteral obligatory osmotic diuretic.
Keep containers tightly closed in a dry, cool and wellventilated place. Links to pubmed are also available for selected references. Mannitol manufacturer in india exporter in india mannitol 10%, mannitol 20%,mannitol 10%, glycerin 10% largest generic manufacturer,drugs,formula,producing mannitol msds,coa, pdf,doc chemical api method according to the present mannitol invention suppliers list,molecular structure,weight,iupac,synonyms for mannitol. Pain and irritation where mannitol systemic goes into the body. Dmannitol cas no 69658 material safety data sheet sds msds. Dmannitol 69658 98 section 4 first aid measures swallowed immediately give a glass of water.
Section 3 hazards identification emergency overview appearance. Material safety data sheet section 1 dmannitol 1 chemical product and company identification msds name. Mannitol selenite broth safety data sheet date of issue 102008. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Mannitol is fully biodegradable and the products of degradation are more toxic. Dmannitol is a simple sugar alcohol and should be readily biodegraded in the environment.
Identification of the substancepreparation and of the companyundertaking. Mannitol is freely filtered by the glomerulus and poorly reabsorbed from the renal tubule, thereby causing an increase in osmolarity of the glomerular filtrate. View product specific information, msds, references and buying faq. Safety data sheets sdss for pharmaceutical products can be accessed by utilizing our pharmaceutical product listing tool and clicking on the product page for which you are interested in obtaining a. Maltitol maltitol side effects applications and uses of maltitol halal certified maltitol kosher certified maltitol is maltitol gluten free maltitol wholesale price, price trend of maltitol where to buy maltitol at the cheapest price.
Canadian ingredient disclosure list no information found section 16 other. Mannitol injection fda prescribing information, side. For the full text of the r phrases mentioned in this section, see section 16 4. When used before or after surgery, a total dose of 1.
Mannitols nonhygroscopic properties, together with a sweet bland taste, make it an excellent base for formulations of chewable tablets in combination with many different actives. Eye if this product comes in contact with eyes wash out immediately with water. Our msds database is an easy to use, do it yourself tool, and best of all. However, the data is provided without any warranty, expressed or implied, regarding its correctness or accuracy.
By standardizing the media employed, the lowdust granule. The information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Other information msds first issued 30052002 msds data.
Weve included the most sought after safety data sheets, and the database just keeps growing. Material safety data sheet 1 mannitol, usp grade exmn 50001 section 1 chemical product and company identification ops diagnostics, llc 291 us highway 22 east. It is a carbohydrate, a sugar alcohol, made from fructose and hydrogen 2,3p. Mannitol is a naturally occurring alcohol found in fruits and vegetables and used as an osmotic diuretic. Search our product to see the coa msds for microbiology products, molecular biology products, animal cell culture, plant tissue culture, chemicals and lab equipments. Clear up spills immediately and dispose of waste safely.
Pharmaceutical products safety data sheets safety data sheets sdss for pharmaceutical products can be accessed by utilizing our pharmaceutical product listing tool and clicking on the product page for which you are interested in obtaining a safety data sheet sds. Mannitol 100 ld50,50022,000 mgkg mice, rats ld50 is the dosage producing 50% mortality. Mannitol, marketed under the brand names aridol and osmitrol, is the generic form of a prescription drug used to reduce pressure in the brain when its elevated. Dmannitol environmental precautions avoid discharge into drains or watercourses or onto the ground. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032. This material safety data sheet does not constitute the guaranty or specifications of the product.
Quality management dossier operational excellence dossier. Nmt twice the area of the principal peak obtained bright light. Osmitrol mannitol dose, indications, adverse effects. Collect powder using special dust vacuum cleaner with particle filter or carefully sweep into suitable waste disposal containers and seal securely. Mannitol 69658 2007118 not listed sodium phosphate, dibasic 7558794 2314487 not listed water 7732185 2317912 not listed additional information. Dmannitol is produced by the catalytic hydrogenation of carbohydrate solutions of glucose andor fructose. Download msds pdf search msds currently available for download bioworld offers dmannitol for your research at low price. Package insert mannitol injection, usp, 25% description. However, many people have no side effects or only have minor side effects. The low dmannitol yield 25 30%, however, asks for the development of alternative procedures.
Mannitol is a naturally occurring sugar alcohol found in animals and plants. Mannitol, usp is chemically designated d mannitol c 6 h 14 o 6, a white crystalline powder or freeflowing granules freely soluble in water. Official label printer friendly view all sections close all sections. Mannitol salt agar is a selective and differential medium for the detection and enumeration of staphylococci from clinical and nonclinical specimens.
Mannitol salt agar contains beef extract and proteose peptone, which makes it very nutritious as they provide essential growth factors and trace nutrients. An estimated bcf of 1 was calculated for dmannitolsrc, using a water solubility of 2. Fastdissolving powders come premixed for quick preparation using neutral liquids. Mannitol e421 is fully biodegradable and the products of degradation are more toxic. This product has been classified in accordance with the hazard criteria of the controlled products regulations and the msds contains all of the information required by those regulations. Contains mannitol 20% wv section iii physical characteristics boiling point. Get a printable copy pdf file of the complete article 1. It is poorly absorbed in the small intestine, so it travels to the large intestine where beneficial intestinal bacteria break it ferment into gases and shortchain fatty acids scfas, which can be absorbed and provide some energy. The resulting mannitol salt agar base is recommended for the isolation of coagulasepositive staphylococci from cosmetics, milk, food and other specimens 10, 5,3,12,11. Transportation information this product is not a regulated material for domestic ground transporation. As a diuretic it can be used to treat patients with intractable edema states, to increase urine flow and flush out debris from the renal tubules in patients with acute tubular necrosis, and to increase toxin excretion in patients with barbiturate, salicylate or bromide intoxication. Dehydrated microbiology culture media cultivate and isolate microorganisms for researching purposes.
The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. A 25% solution of mannitol is recommended since its effectiveness depends on establishing intravascular hyperosmolarity. Mannitol, usp is chemically designated dmannitol c 6 h 14 o 6, a white crystalline powder or freeflowing granules freely soluble in water. Stage 6 harmonization 2 mannitol official august 1, 2015 unspecified impurities.
Dmannitol c6h14o6 was solved from highresolution synchrotron xray powder diffraction data collected on a mixture containing 20% and 80% ww of. If in doubt, contact a poisons information centre or a doctor. Mannitol salt agar safety data sheet date of issue 12022009. A literature survey of the various production methods is given, including some other possible. Dmannitol material safety data sheet cas no 69658 sdsmsds. Many other bacteria except staphylococci are inhibited by 7. D mannitol environmental precautions avoid discharge into drains or watercourses or onto the ground. Mannitol may be useful clinically both as a diuretic and as an obligate extracellular solute. Mannitol mannitol side effects applications and uses of mannitol halal certified mannitol kosher certified mannitol is mannitol gluten free mannitol wholesale price, price trend of mannitol. Mannitol 20% 69658 none none ingredients not precisely identified are proprietary or nonhazardous. Full text full text is available as a scanned copy of the original print version. High fructose corn syrup msds polydextrose msds isomalt msds. Material safety data sheet canadian whmis classifications no information found this product has been classified in accordance with the hazard criteria of the controlled products regulations and the msds contains all of the information required by those regulations.
Material safety data sheet section 1 d mannitol 1 chemical product and company identification msds name. Other information msds first issued 28052002 msds data revised 12. Mannitol manufacturer,exporter, mannitol,manufacturing. Mannitol injection, usp is a parenteral obligatory osmotic diuretic. Safety data sheet northwest missouri state university.
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